spring 2007

h e a l t h   t e c h n o l o g y
Informing the management of patients at risk of thromboembolic events

 

Point-of-care monitoring devices can be effective in the management of patients on long-term oral anticoagulation therapy, resulting in significantly fewer deaths and thromboembolic events, according to a recent health technology assessment report by the Canadian Agency for Drugs and Technologies in Health (CADTH).

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Point-of-care monitoring devices can be effective in the management of patients on long-term oral anticoagulation therapy, resulting in significantly fewer deaths and thromboembolic events, according to a recent health technology assessment report by the Canadian Agency for Drugs and Technologies in Health (CADTH).

The report, Point-of-Care Monitoring Devices for Long-Term Oral Anticoagulation Therapy: Clinical and Cost Effectiveness, involved a systematic review of the clinical and economic literature on the use of these devices, and a Canadian economic analysis.

Portable point-of-care devices enable patients on long-term oral anticoagulation therapy to be monitored in a clinic or at home. The devices use a drop of blood from a fingertip and results are available almost immediately.

The CADTH report may be of interest to administrators of anticoagulation programs who need to know how point-of-care devices used by patients and anticoagulation clinics compare with standard laboratory testing. The report may also be of interest to physicians and patients in rural or remote areas, as well as to patients who may be traveling away from home for extended periods.

Compared with laboratory testing, using point-of-care devices results in better control of anticoagulation status for the monitoring of oral anticoagulation therapy. There were no significant differences in hemorrhagic events. Use of point-of-care devices in anticoagulation clinics results in cost savings for Canada’s publicly funded system compared with conventional testing in laboratory settings.

About one-quarter of the estimated 209,000 patients on oral anticoagulation therapy in Canada’s publicly funded drug programs could be eligible for self-testing or self-management with point-of-care devices. However, education is key for patients, caregivers and health-care providers. Self-testing by patients, compared with laboratory testing, does not seem to be cost saving for the publicly funded health-care system.

This report is available on CADTH’s web site. CADTH welcomes your feedback on the report through the online survey available on this page. You can also contact CADTH’s Liaison Officer for Newfoundland and Labrador. Cindy Mosher  will be the interim Liaison Officer as of March 9, 2007, while Sheila Tucker is on temporary leave.

The Canadian Agency for Drugs and Technologies in Health (CADTH) is a national body that provides Canada’s federal, provincial, and territorial health care decision makers with credible, impartial advice and evidence-based information about the effectiveness and efficiency of drugs and other health technologies.

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